Intravenous mannitol may lead to electrolyte disturbances involving sodium and potassium and resulting in\r\ncardiac dysfunction. This report demonstrates that when mannitol is given during intracranial surgery it can cause\r\nlarge increase potassium ion concentration and decrease in sodium ion concentration in the absence of any other\r\npossible causes. Intraoperative checks of serum electrolyte levels, arterial blood gas analysis and electrocardiogram\r\nmonitoring could be recommended to be done routinely when using mannitol.
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